Tetrapyrroles and derivatives
Abcam (Arg8)-Vasopressin (AVP), Vasopressin receptor agonist, 5MG
MW 1084.2 Da, Purity >95%. (Arg8)-Vasopressin (AVP), Vasopressin receptor agonist. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
Abcam E x endin-4 (E x enatide), GLP-1 receptor agonist, 1MG
MW 4187 Da, Purity >95%. Exendin-4 (Exenatide), GLP-1 receptor agonist. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
Abcam A 943931 dihydrochloride, H4 receptor antagonist, 50MG
MW 368.3 Da, Purity >99%. Potent and selective H4 receptor antagonist (pKi = 7-8). Shows anti-inflammatory and analgesic effects *in vivo.* Orally active.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Edaravone (MCI-186), antio x idant, 50MG
MW 174.2 Da, Purity >99%. Free radical scavenger and potent antioxidant. Inhibits production of reactive oxygen species, apoptosis and the lipoxygenase system.
The product is subject to the following: Abcam Restricted Use Statement
Abcam LY 294002, PI3-kinase inhibitor, 25MG
MW 307.3 Da, Purity >99%. A highly selective inhibitor of phosphatidylinositol 3-kinase (IC₅₀ = 1.4 μM). Selective over a range of other kinases including protein kinase C, protein kinase A, MAPK and PI4- kinase (IC₅₀ > 50 μM).
The product is subject to the following: Abcam Restricted Use Statement
Abcam Bisindolylmaleimide II, PKC inhibitor, 5MG
MW 438.5 Da, Purity >97%. Potent, selective ATP-competitive PKC inhibitor (IC₅₀ values are 0.01, 0.75 and 2 μM for PKC, phosphorylase kinase and PKA respectively). Potent noncompetitive nAChR antagonist (IC₅₀ = 0.03 μM, catecholamine secretion in nicotine-stimulated PC-12 cells). Shows more potent antinicotinic effects than Bisindolylmaleimide IV (ab144208) and V (ab144205). Induces apoptosis and shows antiproliferative effects.
The product is subject to the following: Abcam Restricted Use Statement
Abcam (R)-CPP, NMDA antagonist, 10MG
MW 252.2 Da. Highly potent, competitive NMDA antagonist; more active enantiomer of (RS)-CPP (ab120160). (Ki values are 0.04, 0.3, 0.6 and 2.0 μM at NR1/NR2A, NR1/NR2B, NR1/NR2C and NR1/NR2D, respectively).
The product is subject to the following: Abcam Restricted Use Statement
Abcam Nocodazole, Microtubule inhibitor, 50MG
MW 301.32 Da, Purity >98%. Microtubule inhibitor. Rapidly depolymerises microtubules in vivo and inhibits tubulin polymerisation in vitro. Inhibits mitosis. Also reduces stem cell pluripotency factors Oct 4 and Nanog.
The product is subject to the following: Abcam Restricted Use Statement
Abcam SB 242084 hydrochloride, 5-HT2C antagonist, 10MG
MW 431.3 Da, Purity >98%. Potent, selective 5-HT2C antagonist (pKi values are 9 (5-HT2C), 7 (5-HT2B), 6.8 (5-HT2A), 6.4 (5-HT1A), 6.4 (5-HT1B), 6.4 (5-HT1D), 6 (5-HT1E), <6.1 (5-HT1F), <5.5 (5-HT4), 6 (5-HT6), 6.1 (5-HT7), 6.2 (D2), 6.2 (D3) and <5 (α1)). Blood-brain barrier permeable. Anxiolytic activity *in vivo*.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Phomo x anthone A, apoptotic agent, 1MG
MW 750.7 Da, Purity >97%. Cancer cell selective apoptotic agent. Antibiotic agent. Induces apoptosis in cancer cells lines with 100 fold greater potency than noncancerous lines. Shows immunostimulant effects.
The product is subject to the following: Abcam Restricted Use Statement
Abcam PD 168077 maleate, D4 agonist, 10MG
MW 450.49 g/mol, Purity >98%. Potent, selective D₄ dopamine receptor agonist. Displays >400-fold selectivity over D₂ and >300-fold selectivity over D₃ subtypes (Ki values are 11.9, 2540, and 1050 nM for D₄, D₃, and D₂ receptors, respectively). Reverses object recognition deficits.
The product is subject to the following: Abcam Restricted Use Statement
Abcam 4-Thiouridine, RNA synthesis inhibitor, 5MG
MW 260.27 Da, Purity >99%. Ribonucleoside (Uridine ab143255) analog. Antisense agent. RNA synthesis inhibitor. Modifies oligos slated for RNA. Induces p53 and inhibits proliferation. Metabolically labels RNA for stability studies.
The product is subject to the following: Abcam Restricted Use Statement
Abcam JC-1, Mitochondrial membrane potential dye, 5MG
MW 652.2 Da, Purity >95%. Mitochondrial membrane-potential dye. Exhibits potential-dependent accumulation in mitochondria. Fluorescence emission shift from green (~529 nm) to red (~590 nm). Depolarization is indicated by a decrease in the red/green fluorescence intensity ratio.
The product is subject to the following: Abcam Restricted Use Statement
Abcam UDP-glucose, Highly P2Y14 agonist, 500MG
MW 610.27 Da. Highly potent, endogenous P2Y14 agonist (EC50 = 82 nM). Involved in modulation of gastric function. UDP also available (ab120383).
The product is subject to the following: Abcam Restricted Use Statement
Abcam PDTC (Ammonium pyrrolidinedithiocarbamate), NF-kappaB inhibitor antio x idant, 100MG
MW 164.3 Da. Selective NF-κB inhibitor. Inhibits translation of nitric oxide synthase mRNA to prevent induction. Metal ion chelator and antioxidant. Active in vitro.
The product is subject to the following: Abcam Restricted Use Statement